SERPINB2 wt Allele

Preferred Label : SERPINB2 wt Allele;

NCIt synonyms : PAI2; PLANH2; Serine (or Cysteine) Proteinase Inhibitor, Clade B (Ovalbumin), Member 2 wt Allele;

NCIt definition : Human SERPINB2 wild-type allele is located in the vicinity of 18q21.3 and is approximately 16 kb in length. This allele, which encodes plasminogen activator inhibitor 2 protein, is involved in the inhibition of urokinase-type plasminogen activator.;

NCIt note : Up-regulation of SERPINB2 gene expression is associated with inhibition of metastasis and a better prognosis for cancer patients. This gene is expressed in keratinocytes, macrophages, monocytes, placenta, and the trophoblast.;

GenBank Accession Number : NM_002575;

Details

Origin ID

C51406;

UMLS CUI

C1705218;

Automatic exact mappings (from CISMeF team)
- Plasminogen activator inhibitor 2 [LOINC component]
- Plasminogen activator inhibitor-2 (substance) [SNOMED CT concept]
- Serpin peptidase inhibitor, clade b (ovalbumin), member 2 [OMIM gene]
- plasminogen activator inhibitor 2 [MeSH Descriptor]
OMIM relation
- Serpin peptidase inhibitor, clade b (ovalbumin), member 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 18q21.3 [NCIt concept]
gene_plays_role_in_process
- Enzyme Inhibition [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients