Alpha-1-Antitrypsin

Preferred Label : Alpha-1-Antitrypsin;

NCIt synonyms : Alpha-1 Protease Inhibitor; Serine (or Cysteine) Proteinase Inhibitor, Clade A, Member 1; Serpin Peptidase Inhibitor Clade A Member 1; Serpin Family A Member 1; Serpin A1; Alpha-1-Antiproteinase; Alpha1AT; Anti-Elastase; Alpha-1 Antitrypsin; Protease Inhibitor 1; SERPINA1;

NCIt definition : Alpha-1-antitrypsin (418 aa, 47 kDa) is encoded by the human SERPINA1 gene. This protein plays a role in regulation of proteolysis.;

Details

Origin ID

C105012;

UMLS CUI

C1455316;

Currated CISMeF NLP mapping
- Alpha 1 antitrypsin [LOINC component]
- alpha 1-Antitrypsin [MeSH Descriptor]
- alpha 1-Antitrypsin [MeSH concept]
OMIM relation
- Serpin peptidase inhibitor, clade a, member 1 [OMIM gene]
See also inter- (CISMeF)
- Alpha-1 anti-trypsin [MedDRA Preferred Term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Alpha 1 antitrypsin [LOINC component]
- Alpha1-proteinase inhibitor (product) [Inactive SNOMED CT concept]
- Human alpha1 proteinase inhibitor (substance) [SNOMED CT concept]
- SERPINA1 protein, human [MeSH concept]
- SERPINA1 protein, human [MeSH Supplementary Concept]
- alfa1 antitrypsin [ATC Code]
- alpha 1-Antitrypsin [MeSH Descriptor]
- alpha 1-Antitrypsin [MeSH concept]
- alpha1 anti-trypsin [SNOMED Notion]
Validated automatic mappings to BTNT
- Human alpha1 proteinase inhibitor (substance) [SNOMED CT concept]
- Human alpha1-proteinase inhibitor [SMS substance]
- alfa1 antitrypsin [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Inhibitor Gene [NCIt concept]
- Proteinase Inhibitor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- SERPINA1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Serpin [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_plays_role_in_biological_process
- Enzyme Inhibition [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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