Preferred Label : alpha 1-Antitrypsin;
MeSH definition : Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL
ELASTASE; and other PROTEOLYTIC ENZYMES.;
MeSH synonym : trypsin inhibitor, alpha 1 antitrypsin; alpha 1-antiproteinase; antiprotease, alpha 1; alpha 1 antiprotease; inhibitor, alpha 1-proteinase; inhibitor, alpha 1-protease; alpha 1 proteinase inhibitor; alpha 1-proteinase inhibitor; 1-antiproteinase, alpha; a1pi; alpha 1 protease inhibitor; alpha 1 antiproteinase; alpha 1-protease inhibitor; trypsin inhibitor, alpha 1-antitrypsin; Serpin A1; alpha 1 antitrypsin;
CISMeF synonym : alpha 1-proteinase inhibitor f; alpha 1 proteinase inhibitor s; alpha 1 proteinase inhibitor f; alpha 1-proteinase inhibitor s;
MeSH hyponym : prolastin; zemaira;
Is substance : O;
medicament (CISMeF) : O;
Origin ID : D000515;
UMLS CUI : C0002191;
ATC code(s)
Allowable qualifiers
Pharmacological action(s)
Record concept(s)
Related MeSH Supplementary Concept(s)
- VIR-353 [MeSH Supplementary Concept]
Related MeSH term(s)
See also
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
Plasma glycoprotein member of the serpin superfamily which inhibits TRYPSIN; NEUTROPHIL
ELASTASE; and other PROTEOLYTIC ENZYMES.
https://www.chu-lyon.fr/deficit-en-alpha-1-antitrypsine-aat
2025
France
popular works
alpha 1-Antitrypsin
aortic aneurysm, thoracic
alpha 1-antitrypsin deficiency
alpha-1-antitrypsin deficiency
---
https://www.has-sante.fr/jcms/p_3499784/fr/prolastin-alpha-1-antitrypsine-humaine-deficit-en-alpha-1-antitrypsine
2024
false
false
false
France
insurance, health, reimbursement
alfa1 antitrypsin
alpha 1-Antitrypsin
alpha 1-antitrypsin deficiency
Product containing only human alpha1 proteinase inhibitor in parenteral dose form
(medicinal product form)
evaluation of the transparency committee
---
https://www.inesss.qc.ca/publications/repertoire-des-publications/publication/zemairamc-deficit-congenital-en-alpha1-antitrypsine.html
2023
Canada
drug evaluation
zemaira
alpha 1-Antitrypsin
---
https://www.inesss.qc.ca/publications/repertoire-des-publications/publication/prolastinmc-c-liquid-deficit-congenital-en-alpha1-antitrypsine.html
2023
Canada
drug evaluation
alpha 1-Antitrypsin
prolastin
liquid substance, nos
---
https://www.inesss.qc.ca/publications/repertoire-des-publications/publication/glassiamc-deficit-congenital-en-alpha1-antitrypsine.html
2023
Canada
drug evaluation
alpha 1-Antitrypsin
---
https://www.has-sante.fr/jcms/p_3372787/fr/rymphysia-alpha-1-antitrypsine-humaine
2022
false
false
false
France
treatment outcome
insurance, health, reimbursement
infusions, intravenous
Product containing precisely human alpha1 proteinase inhibitor 1 gram/1 vial powder
for conventional release solution for injection (clinical drug)
Product containing precisely human alpha1 proteinase inhibitor 500 milligram/1 vial
powder for conventional release solution for injection (clinical drug)
adult
alpha 1-antitrypsin deficiency
alfa1 antitrypsin
Pulmonary emphysema in alpha-1 primary immunodeficiency deficiency (disorder)
evaluation of the transparency committee
alpha 1-Antitrypsin
---
http://agence-prd.ansm.sante.fr/php/ecodex/extrait.php?specid=64197553
2021
false
false
false
France
French
alpha 1-Antitrypsin
summary of product characteristics
package leaflet
alpha 1-antitrypsin deficiency
alfa1 antitrypsin
infusions, intravenous
---
Alpha1-proteinase inhibitor (Human) - Zemaira
https://cadth.ca/fr/inhibiteur-de-lalpha1-proteinase-humain
2021
false
false
false
Canada
French
English
drug evaluation
insurance, health, reimbursement
alpha 1-Antitrypsin
adult
alpha 1-antitrypsin deficiency
---
https://www.has-sante.fr/jcms/p_3195773/fr/prolastin
2020
false
false
false
France
French
evaluation of the transparency committee
insurance, health, reimbursement
treatment outcome
alpha 1-Antitrypsin
alpha 1-Antitrypsin
alfa1 antitrypsin
alpha 1-antitrypsin deficiency
---
http://circulaire.legifrance.gouv.fr/index.php?action=afficherCirculaire&hit=1&r=43135
2018
false
false
false
false
France
French
legislation
mars
solvent, nos
relative
alpha 1-Antitrypsin
solutions
Portal vein air
patient care management
injections
hospitalization
Induced fracture
transitory
injection, nos
hospital admission, nos
SERPINA1 protein, human
tension
Solutions
Powders
powders
hypertension
laboratories
Injection moulding
solution, nos
homo sapiens
major
Liver abscess
humans
solutions
---
https://www.has-sante.fr/portail/jcms/c_2751858/fr/alfalastin-alpha-1-antitrypsine-humaine-inhibiteur-de-proteinases
https://www.has-sante.fr/portail/jcms/c_2751858/fr/alfalastin
2017
false
false
false
France
French
evaluation of the transparency committee
guidelines for drug use
treatment outcome
injections, intravenous
alfa1 antitrypsin
serine proteinase inhibitors
serine proteinase inhibitors
alpha 1-antitrypsin deficiency
alpha 1-Antitrypsin
alpha 1-Antitrypsin
pulmonary emphysema
Pulmonary emphysema in alpha-1 primary immunodeficiency deficiency (disorder)
---
http://www.has-sante.fr/portail/jcms/c_2610146/fr/respreeza
http://www.has-sante.fr/portail/jcms/c_2610146/fr/respreeza-alpha-1-antitrypsine-humaine-inhibiteur-de-proteinases
2016
false
false
false
France
French
treatment outcome
alfa1 antitrypsin
SERPINA1 protein, human
product surveillance, postmarketing
adult
alpha 1-antitrypsin deficiency
infusions, intravenous
Human alpha1 proteinase inhibitor (product)
evaluation of the transparency committee
pulmonary emphysema
guidelines for drug use
protease inhibitors
Pulmonary emphysema in alpha-1 primary immunodeficiency deficiency (disorder)
alpha 1-Antitrypsin
---
https://www.ema.europa.eu/medicines/human/EPAR/Respreeza
2015
false
false
false
United Kingdom
French
English
treatment outcome
syndication feed
summary of product characteristics
package leaflet
drug evaluation
drug approval
europe
alfa1 antitrypsin
SERPINA1 protein, human
SERPINA1 protein, human
product surveillance, postmarketing
drug monitoring
adult
alpha 1-antitrypsin deficiency
infusions, intravenous
Human alpha1 proteinase inhibitor (product)
pregnancy
breast feeding
drug evaluation, preclinical
pulmonary emphysema
Pulmonary emphysema in alpha-1 primary immunodeficiency deficiency (disorder)
alpha 1-Antitrypsin
alpha 1-Antitrypsin
---
https://www.cadth.ca/sites/default/files/pdf/397_Prolastin_tr_f.pdf
https://www.cadth.ca/sites/default/files/pdf/397_Prolastin_tr_appendices_f.pdf
https://www.cadth.ca/fr/linhibiteur-dalpha1-proteinase-humain-dans-le-deficit-en-alpha1-antitrypsine-aat
2006
true
Canada
French
alpha 1-Antitrypsin
alpha 1-antitrypsin deficiency
pulmonary disease, chronic obstructive
drug evaluation
---
http://www.has-sante.fr/portail/jcms/c_247599/alfalastin-ct-2029
http://www.has-sante.fr/portail/jcms/c_601291/alfalastin-ct-2029-english
http://www.has-sante.fr/portail/display.jsp?id=c_401015
2006
false
France
English
French
Pulmonary emphysema in alpha-1 primary immunodeficiency deficiency (disorder)
alpha 1-Antitrypsin
alpha 1-antitrypsin deficiency
alpha 1-antitrypsin deficiency
pulmonary emphysema
injections, intravenous
treatment outcome
serine proteinase inhibitors
alfa1 antitrypsin
evaluation of the transparency committee
---