TIMP2 wt Allele

Preferred Label : TIMP2 wt Allele;

NCIt synonyms : Tissue Inhibitor of Metalloproteinase 2 wt Allele;

NCIt definition : Human TIMP2 wild-type allele is located in the vicinity of 17q25 and is approximately 72kb in length. This allele, which encodes metalloproteinase inhibitor 2 protein, plays a role in extracellular matrix maintenance.;

NCIt note : Gene_Belongs_To_Family: TIMP Family; Gene_Promoter/Enhancer_Contains: Sp1, AP2, AP1, PEA3 Regulatory Elements; Gene_Has_Function: Matrix Metalloproteinase Inhibitor, Extracellular Matrix Degradation, Connective Tissue Remodeling; Gene_Produces_Alternate_Transcripts: 1.2-kb, 3.8-kb;

GenBank Accession Number : NM_003255;

Details

Origin ID

C52120;

UMLS CUI

C1710297;

OMIM relation
- Tissue inhibitor of metalloproteinase 2 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q25 [NCIt concept]
gene_is_element_in_pathway
- Inhibition of Matrix Metalloproteinases Pathway [NCIt concept]
gene_plays_role_in_process
- Enzyme Inhibition [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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