Preferred Label : Cystatin Family Gene;
NCIt synonyms : Cystatin 2 Family Gene;
NCIt definition : Cystatin Family Genes encode (Type 2) Cystatin proteins, secreted, tight, reversible,
competitive inhibitors of cysteine proteinases that contain multiple cystatin-like
sequences and have 2 intrachain disulfide bonds. Cystatin Superfamily Genes comprise
three subfamilies that display structural and/or functional similarities: Stefins
(Type 1 Cystatins), Cystatins (Type 2 Cystatins), and Kininogens. Some members are
active cysteine protease inhibitors; others have lost or never acquired inhibitory
activity. (NCI);
Origin ID : C20727;
UMLS CUI : C1333185;
Semantic type(s)
- gene_found_in_organism
- gene_plays_role_in_process
