NCIt synonyms : PS20; WAP Four-Disulfide Core Domain 1 wt Allele; Prostate Stromal Protein, 20-kD, Rat, Homolog Of Gene;
NCIt definition : Human WFDC1 wild-type allele is located in the vicinity of 16q24.3 and is approximately
35 kb in length. This allele, which encodes WAP four-disulfide core domain protein
1, plays a role in the negative regulation of cell growth. WFDC1 gene expression is
down-regulated in certain cancers such as prostate cancer.;
NCIt note : The WFDC1 gene is a candidate tumor suppressor gene.;