Serpin B4 - CISMeF

Preferred Label : Serpin B4;

NCIt synonyms : SCCA-2; Peptidase Inhibitor 11; Leupin; Squamous Cell Carcinoma Antigen 2; SERPINB4; PI-11;

NCIt definition : Serpin B4 (390 aa, 45 kDa) is encoded by the human SERPINB4 gene. This protein plays a role in the inhibition of protease activity for enzymes such as granzyme M.;

NCIt note : Serpin B4 can be proteolytically processed into smaller fragments that aggregate to form an autoantigen in psoriasis. (EntrezGene);

Details

Origin ID

C148326;

UMLS CUI

C1451613;

Automatic exact mappings (from CISMeF team)
- Serpin peptidase inhibitor, clade b (ovalbumin), member 4 [OMIM gene]
- leupin [MeSH Supplementary Concept]
- leupin [MeSH concept]
- serpin family B member 4 [HGNC gene]
- squamous cell carcinoma antigen 2 [MeSH concept]
- squamous cell carcinoma-related antigen [MeSH Supplementary Concept]
OMIM relation
- Serpin peptidase inhibitor, clade b (ovalbumin), member 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- SERPINB4 protein, human [MeSH concept]
Validated automatic mappings to BTNT
- SERPINB4 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Inhibitor Gene [NCIt concept]
- Proteinase Inhibitor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- SERPINB4 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_chemical_classification
- Serpin [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Amoebiasis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Enzyme Inhibition [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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