TIMP1 wt Allele

Preferred Label : TIMP1 wt Allele;

NCIt synonyms : TIMP; Tissue Inhibitor of Metalloproteinase 1 (Erythroid Potentiating Activity, Collagenase Inhibitor) wt Allele; CLGI; EPA; HCI; EPO;

NCIt definition : Human TIMP1 wild-type allele is located within Xp11.3-p11.23 and is 4.5 kb in length. This allele, which encodes metalloproteinase inhibitor 1 protein, is involved in mediation of both extracellular matrix remodeling and cellular proliferation.;

NCIt note : Gene_Has_Function: Growth Factor, Metalloendoprotease Inhibitor, Connective Tissue Remodeling, Extracellular Matrix Degradation; Gene_Belongs_To_Family: TIMP Family;

GenBank Accession Number : NM_003254;

Details

Origin ID

C52119;

UMLS CUI

C1705819;

False automatic mappings
- EPO [ICD-11 Extension code]
- Epichlorohydrin [LOINC component]
OMIM relation
- Tissue inhibitor of metalloproteinase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- Xp11.3-p11.23 [NCIt concept]
gene_is_element_in_pathway
- Inhibition of Matrix Metalloproteinases Pathway [NCIt concept]
gene_plays_role_in_process
- Enzyme Inhibition [NCIt concept]
- Erythropoiesis [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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