" /> Thioguanine - CISMeF





Preferred Label : Thioguanine;

NCIt synonyms : 6-TG; 2-Amino-6-purinethiol; 2-Aminopurin-6-thiol; 2-Amino 6MP; 6-Thioguanine; 6-Mercapto-2-aminopurine; 6 Thioguanine; 6 Mercaptoguanine; 2-Aminopurine-6(1H)-thione; Tioguanin; Tioguanine; Thioguanine Hemihydrate; 2-Aminopurine-6-thiol Hemihydrate; Thioguanine Hydrate;

NCIt related terms : Lanvis; 2-Aminopurine-6-thiol; 6-Mercaptoguanine; 6H-Purine-6-thione, 2-amino-1,7-dihydro- (9CI); 2-Amino-1,7-dihydro-6H-purine-6-thione; 2-Mercapto-6-aminopurine; 2-Amino-6-mercaptopurine; X 27; 6-Amino-2-mercaptopurine; Tabloid; Wellcome U3B; BW 5071;

NCIt definition : A synthetic guanosine analogue antimetabolite. Phosphorylated by hypoxanthine-guanine phosphoribosyltransferase, thioguanine incorporates into DNA and RNA, resulting in inhibition of DNA and RNA syntheses and cell death. This agent also inhibits glutamine-5-phosphoribosylpyrophosphate amidotransferase, thereby inhibiting purine synthesis. (NCI04);

Alternative definition : NCI-GLOSS: An anticancer drug that belongs to the family of drugs called antimetabolites.;

UNII : FTK8U1GZNX;

InChIKey : VOXBZHOHGGBLCQ-UHFFFAOYSA-N;

CAS number : 5580-03-0;

Drug name : Lanvis; Tabloid;

Molecule name : BW 5071; X 27; WR-1141; Wellcome U3B;

Chemical formula : C5H5N5S.H2O;

NSC code : 752;

Codes from synonyms : CDR0000046765; 06268; NSC0000752; NSC0052758; 489;

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29/05/2025


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