Amidophosphoribosyltransferase

Preferred Label : Amidophosphoribosyltransferase;

NCIt synonyms : Phosphoribosyldiphosphate 5-amidotransferase; Glutamine PRPP Amidotransferase; Glutamine Phosphoribosylpyrophosphatate Amidotransferase; EC 2.4.2.14; PPAT; GPAT; Phosphoribosyl Pyrophosphate Amidotransferase; ATase;

NCIt definition : Amidophosphoribosyltransferase (517 aa, 57 kDa) is encoded by the human PPAT gene. This protein is involved in purine biosynthesis.;

Details

Origin ID

C45562;

UMLS CUI

C5441689;

Currated CISMeF NLP mapping
- Amidophosphoribosyltransferase (substance) [SNOMED CT concept]
- amidophosphoribosyltransferase [SNOMED Notion]
OMIM relation
- Phosphoribosylpyrophosphate amidotransferase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Amidophosphoribosyltransferase (substance) [SNOMED CT concept]
- amidophosphoribosyltransferase [MeSH Descriptor]
- amidophosphoribosyltransferase [MeSH concept]
- amidophosphoribosyltransferase [SNOMED Notion]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- PPAT Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Thioguanine [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alanine, Aspartate and Glutamate Metabolism Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Nucleotide Biosynthesis Process [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients