Heparin Cofactor 2

Preferred Label : Heparin Cofactor 2;

NCIt synonyms : Heparin Cofactor II; HC-II; Protease Inhibitor Leuserpin-2; Leuserpin-2; Serpin D1; HLS2; Leuserpin 2;

NCIt definition : Heparin cofactor 2 (499 aa, 57 kDa) is encoded by the human SERPIND1 gene. This protein plays a role in the glycosaminoglycan-dependent inhibition of thrombin.;

Details

Origin ID

C113637;

UMLS CUI

C2713376;

Automatic exact mappings (from CISMeF team)
- Heparin cofactor II [OMIM gene]
- Hydrolethalus syndrome 2 [OMIM Phenotype]
- SERPIND1 protein, human [MeSH Supplementary Concept]
- hydrolethalus syndrome 2 [DO Concept]
- serpin family D member 1 [HGNC gene]
Currated CISMeF NLP mapping
- Heparin cofactor II [LOINC component]
- Heparin cofactor II (substance) [SNOMED CT concept]
- heparin cofactor II [MeSH concept]
- heparin cofactor II [MeSH Descriptor]
- heparin cofactor ii [SNOMED Notion]
OMIM relation
- Heparin cofactor II [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Heparin cofactor II (substance) [SNOMED CT concept]
- SERPIND1 protein, human [MeSH concept]
- SERPIND1 protein, human [MeSH Supplementary Concept]
- heparin cofactor II [MeSH Descriptor]
- heparin cofactor II [MeSH concept]
- heparin cofactor ii [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Inhibitor Gene [NCIt concept]
- Proteinase Inhibitor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- SERPIND1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Serpin [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Complement and Coagulation Cascade [NCIt concept]
gene_product_plays_role_in_biological_process
- Coagulation Process [NCIt concept]
- Enzyme Inhibition [NCIt concept]
- Heparin Binding [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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