heparin cofactor II

Preferred Label : heparin cofactor II;

MeSH definition : A sulfated plasma protein with a MW of approximately 66kDa that resembles ANTITHROMBIN III. The protein is an inhibitor of thrombin in plasma and is activated by dermatan sulfate or heparin. It is a member of the serpin superfamily.;

MeSH synonym : Serpin D1; Protease Inhibitor Leuserpin 2; heparin co-factor ii; heparin co factor ii; Heparin Cofactor 2; leuserpin 2;

CISMeF synonym : cofactor ii, heparin; co-factor ii, heparin;

MeSH CAS label : heparin cofactor II;

Registry Number MeSH : 81604-65-1;

Is substance : O;

Details

Origin ID

D015844;

UMLS CUI

C0019137;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
False automatic mappings
- antithrombin [Substance BNPC]
- heparin cofactor i [SNOMED Notion]
Indexing information
- intimatan [MeSH Supplementary Concept]
Pharmacological action(s)
- antithrombins [MeSH Descriptor]
Record concept(s)
- heparin cofactor II [MeSH concept]
Related MeSH Supplementary Concept(s)
- SERPIND1 protein, human [MeSH Supplementary Concept]
- Serpind1 protein, mouse [MeSH Supplementary Concept]
- Serpind1 protein, rat [MeSH Supplementary Concept]
- heparin cofactor II deficiency [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- heparin [MeSH Descriptor]
See also inter- (CISMeF)
- Heparin cofactor II [OMIM gene]
- serpin family D member 1 [HGNC gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Heparin Cofactor 2 [NCIt concept]
- Heparin cofactor II [LOINC component]
- Heparin cofactor II (substance) [SNOMED CT concept]
- heparin cofactor ii [SNOMED Notion]
Validated automatic mappings to NTBT
- Heparin cofactor (substance) [SNOMED CT concept]
- heparin cofactor, nos [SNOMED Notion]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients