antithrombins - CISMeF

Preferred Label : antithrombins;

MeSH definition : Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.;

MeSH synonym : direct thrombin inhibitors; thrombin inhibitors, direct; direct antithrombins; antithrombins, direct; Direct Antithrombin; Antithrombin, Direct; Direct Thrombin Inhibitor; Inhibitor, Direct Thrombin; Thrombin Inhibitor, Direct; Antithrombin;

MeSH annotation : ANTITHROMBIN PROTEINS is also available;

Wikipedia link : https://en.wikipedia.org/wiki/Antithrombin;

Is substance : O;

action pharmacologique : O;

Details

Origin ID

D000991;

UMLS CUI

C0003440;

ATC code(s)
- direct thrombin inhibitors [ATC Code]
Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- economics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Substance with direct thrombin inhibitor mechanism of action (substance) [SNOMED CT concept]
- direct thrombin inhibitors [ATC Code]
Indexing information
- CDSO3 heparin [MeSH Supplementary Concept]
- CVS995 protein, human [MeSH Supplementary Concept]
- idraparinux [MeSH Supplementary Concept]
Manual NTBT mappings (CISMeF)
- Multiple congenital anomalies/dysmorphic syndrome-intellectual disability [ORDO Disease]
- Rare constitutional hemolytic anemia [ORDO Disease]
- Rare genetic syndromic intellectual disability [ORDO Disease]
- Rare syndromic intellectual disability [ORDO Disease]
Record concept(s)
- antithrombins [MeSH concept]
See also (suggested by CISMeF)
- anticoagulants [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
Substance(s)
- 6-methyl-1,2,3,5-tetrahydroimidazo(2,1-b)quinazolin-2-one hydrochloride [MeSH Supplementary Concept]
- Dabigatran [MeSH Descriptor]
- HY023016 [MeSH Supplementary Concept]
- SDZ MTH 958 [MeSH Supplementary Concept]
- antithrombin III [MeSH Descriptor]
- antithrombin proteins [MeSH Descriptor]
- argatroban [MeSH Supplementary Concept]
- bivalirudin [MeSH Supplementary Concept]
- heparin cofactor II [MeSH Descriptor]
- hirudins [MeSH Descriptor]
- inogatran [MeSH Supplementary Concept]
- lepirudin [MeSH Supplementary Concept]
- melagatran [MeSH Supplementary Concept]
- pyragrel [MeSH Supplementary Concept]
- ximelagatran [MeSH Supplementary Concept]
UMLS correspondences (same concept)
- Antithrombin (substance) [Inactive SNOMED CT concept]
- Direct Thrombin Inhibitor [NCIt concept]
- Direct Thrombin Inhibitors [LOINC hierarchical part]
- Product containing direct thrombin inhibitor (product) [SNOMED CT concept]
- Substance with direct thrombin inhibitor mechanism of action (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

Main resources

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