factor xa - CISMeF

Preferred Label : factor xa;

MeSH definition : Activated form of factor X that participates in both the intrinsic and extrinsic pathways of blood coagulation. It catalyzes the conversion of prothrombin to thrombin in conjunction with other cofactors.;

MeSH synonym : factor x, activated; coagulation factor xa; autoprothrombin c; factor xa, coagulation; thrombokinase; activated factor x; blood coagulation factor x, activated; Factor Ten A; Factor 10A;

CISMeF synonym : xa, coagulation factor;

Registry Number MeSH : EC 3.4.21.6;

MeSH annotation : /defic FACTOR X DEFICIENCY;

Wikipedia link : https://en.wikipedia.org/wiki/Thrombokinase;

Is substance : O;

UNII : EC 3.4.21.6;

Details

Origin ID

D015951;

UMLS CUI

C0015520;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analogs and derivatives [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Anti factor Xa (substance) [SNOMED CT concept]
- Coagulation Factor X [NCIt concept]
- Coagulation factor X (substance) [SNOMED CT concept]
- Coagulation factor X activity [LOINC component]
- Coagulation factor Xa (substance) [SNOMED CT concept]
- blood-coagulation factor ix [Substance BNPC]
- blood-coagulation factor x [Substance BNPC]
- coagulation factor x [SNOMED Notion]
- coagulation factor xa [SNOMED Notion]
- obsolete blood coagulation factor activity [GO term]
- obsolete coagulation factor Xa activity [GO term]
- serine-type endopeptidase activity [GO term]
Indexing information
- 1-(1-(3-((6-chloronaphthalen-2-yl)sulfonyl)-2-hydroxypropanoyl)piperidin-4-yl)tetrahydropyrimidin-2(1H)-one [MeSH Supplementary Concept]
- 1-(1-amino-7-isoquinolyl)-N-(2'-(aminosulfonyl)-1,1'-biphenyl-4-yl)-3-methyl-1H-pyrazole-5-carboxamide [MeSH Supplementary Concept]
- 1-(2,2-difluoroethyl)pyrrolidine-3,4-dicarboxylic acid 3-((5-chloropyridin-2-yl)amide) 4-((2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl)amide) [MeSH Supplementary Concept]
- 1-(3-(aminomethyl)phenyl)-N-(3-fluoro-2'-(methylsulfonyl)(1,1'-biphenyl)-4-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide [MeSH Supplementary Concept]
- 1-(3-aminobenzisoxazol-5'-yl)-3-trifluoromethyl-6-(2'-(3-hydroxy-N-pyrrolidinyl)methyl-(1,1')-biphen-4-yl)-1,4,5,6-tetrahydropyrazolo-(3,4-c)-pyridin-7-one [MeSH Supplementary Concept]
- 2-(1-(3-((6-chloronaphthalen-2-yl)sulfonyl)propanoyl)piperidin-4-yl)-5-methyl-1,2-dihydro-3H-imidazo(1,5-c)imidazol-3-one [MeSH Supplementary Concept]
- 2-(4-(dimethylamino)benzoylamino)-5-methanesulfonylamino-N'-(4-methoxyphenyl)benzamide [MeSH Supplementary Concept]
- 2-(5-chlorothien-2-yl)-N-(1-(1-methyl-2-(morpholin-4-yl)-2-oxoethyl)-2-oxopyrrolidin-3-yl)ethenesulfonamide [MeSH Supplementary Concept]
- 2-carbamoyl-4-((6-chloronaphthalen-2-yl)sulfonyl)-1-((5-methyl-4,5,6,7-tetrahydrothiazolo(5,4-c)pyridin-2-yl)carbonyl)piperazine [MeSH Supplementary Concept]
- 3,3'-(3,5-difluoro-4-methyl-2,6-pyridinediylbis(oxy))bis(benzenecarbox(imide)amide) [MeSH Supplementary Concept]
- 3-(3-(aminoiminomethyl)phenyl)-5-(((5--(2-(aminosulfonyl)phenyl)-2-pyridinyl)amino)carbonyl)-4,5-dihydro-5-isoxazoleacetic acid methyl ester [MeSH Supplementary Concept]
- 3-(4-(5-(2,6-dimethylpiperidin-1-yl)pentyl)-3-oxo-3,4-dihydroxyquinoxalin-2-yl)benzamidine [MeSH Supplementary Concept]
- 3-(4-(5-(2,6-dimethyltetrahydro-1(2H)-pyridinyl)pentyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)-1-benzenecarboximidamide [MeSH Supplementary Concept]
- 3-chloro-N-(4-chloro-2-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-methoxyphenyl)-4-(((4,5-dihydro-2-oxazolyl)methylamino)methyl)-2-thiophenecarboxamide [MeSH Supplementary Concept]
- 3-chloro-N-(4-chloro-2-(((5-chloro-2-pyridinyl)amino)carbonyl)-6-methoxyphenyl)-4-((methylamino)methyl)-2-thiophenecarboxamide [MeSH Supplementary Concept]
- 4-((2-amidino-1,2,3,4-tetrahydroisoquinolin-7-yloxy)methyl)-1-(4-pyridinyl)piperidine-4-carboxylic acid monomethanesulfonate trihydrate [MeSH Supplementary Concept]
- 5-chlorothiophene-2-carboxylic acid (2-(2-methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino)-3-(4-methylpiperazin-1-yl)-3-oxopropyl)amide [MeSH Supplementary Concept]
- 6-(dimethylcarbamoyl)nicotinoyl guanidine [MeSH Supplementary Concept]
- 6-chloromethyl-3-(2,5-dichlorophenoxycarbonyl)-2-benzopyrone [MeSH Supplementary Concept]
- Amblyomin-X protein, amblyomma cajennense [MeSH Supplementary Concept]
- BMS 269223 [MeSH Supplementary Concept]
- BnSO(2)-D-Arg-Gly-Arg-ketothiazole [MeSH Supplementary Concept]
- DPC 602 [MeSH Supplementary Concept]
- FX 2212 [MeSH Supplementary Concept]
- ITF 1331 [MeSH Supplementary Concept]
- N(2)-(4-(dimethylamino)benzoyl)-4-hydroxy-N(1)-(4-methoxybenzoyl)-1,2-benzenediamine [MeSH Supplementary Concept]
- N-(4-(1-(acetimidoyl)piperidin-4-yloxy)-3-carbamoylphenyl)-N-(3-(3-amidinophenyl)-2-fluoro-2-propenyl)sulfamoylacetic acid [MeSH Supplementary Concept]
- N-(4-chlorophenyl)-N-(2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl)-4-methoxypyrrolidiine-1,2-dicarboxamide [MeSH Supplementary Concept]
- PD0313052 [MeSH Supplementary Concept]
- RPR 120844 [MeSH Supplementary Concept]
- RPR 130737 [MeSH Supplementary Concept]
- RPR 208566 [MeSH Supplementary Concept]
- RPR 209685 [MeSH Supplementary Concept]
- RWJ 445167 [MeSH Supplementary Concept]
- SE 170 [MeSH Supplementary Concept]
- SEL 2711 [MeSH Supplementary Concept]
- SF 324 [MeSH Supplementary Concept]
- SV-66 protein, simulium vittatum [MeSH Supplementary Concept]
- WX-FX4 compound [MeSH Supplementary Concept]
- YM 60828 [MeSH Supplementary Concept]
- ZK 805412 [MeSH Supplementary Concept]
- ZK 806299 [MeSH Supplementary Concept]
- alpha-(3-amidinylphenoxy)-2-bromo-N-(5-(pyrrolidin-1-ylcarbonyl)phenyl)phenylacetamide [MeSH Supplementary Concept]
- darexaban [MeSH Supplementary Concept]
- edoxaban [MeSH Supplementary Concept]
- eisenstasin [MeSH Supplementary Concept]
- factor xa, Glu-Gly-Arg- [MeSH Supplementary Concept]
- isoleucyl-glutamyl-glycyl-arginine chloromethyl ketone [MeSH Supplementary Concept]
- lefaxin [MeSH Supplementary Concept]
- lipoprotein-associated coagulation inhibitor [MeSH Supplementary Concept]
- lufaxin protein, lutzomyia longipalpis [MeSH Supplementary Concept]
- otamixaban [MeSH Supplementary Concept]
- therostasin protein, theromyzon tessulatum [MeSH Supplementary Concept]
- tick anticoagulant peptide [MeSH Supplementary Concept]
Record concept(s)
- factor xa [MeSH concept]
Related MeSH Supplementary Concept(s)
- PRT064445 [MeSH Supplementary Concept]
- Xai-K protein [MeSH Supplementary Concept]
- dansyl-glutamyl-glycyl-arginyl chloromethyl ketone-treated factor xa [MeSH Supplementary Concept]
- factor rXai [MeSH Supplementary Concept]
- factor xa, Glu-Gly-Arg- [MeSH Supplementary Concept]
- factor xa, des(1-44)- [MeSH Supplementary Concept]
- factor xa, des(1-45)- [MeSH Supplementary Concept]
- glutamyl-glycyl-arginyl chloromethyl ketone inactivated human factor xa [MeSH Supplementary Concept]
- prothrombinase complex [MeSH Supplementary Concept]
Related MeSH term(s)
- Factor Xa Inhibitors [MeSH Descriptor]
- factor x deficiency [MeSH Descriptor]
See also
- coagulants [MeSH Descriptor]
See also (suggested by CISMeF)
- Factor Xa Inhibitors [MeSH Descriptor]
See also inter- (CISMeF)
- Factor X Activity Measurement [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Coagulation factor Xa (substance) [SNOMED CT concept]
- Product containing coagulation factor Xa (medicinal product) [SNOMED CT concept]
- coagulation factor xa [SNOMED Notion]
Validated automatic mappings to NTBT
- Coagulation factor X (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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