Coagulation Factor X

Preferred Label : Coagulation Factor X;

NCIt synonyms : EC 3.4.21.6; Stuart-Prower Factor; Factor X; Prothrombinase; Blood Coagulation Factor X; Stuart Factor; F10;

NCIt definition : Coagulation factor X (488 aa, 55 kDa) is encoded by the human F10 gene. This protein is involved in proteolysis and blood coagulation.;

NCIt note : Coagulation factor X can be cleaved into three products, factor X light chain, factor X heavy chain and activated factor Xa heavy chain. (UniProt);

Details

Origin ID

C76142;

UMLS CUI

C5552804;

Currated CISMeF NLP mapping
- Coagulation factor X (substance) [SNOMED CT concept]
- blood-coagulation factor x [Substance BNPC]
- coagulation factor x [SNOMED Notion]
- factor X [MeSH Descriptor]
- factor X [MeSH concept]
OMIM relation
- Factor X deficiency [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
Validated automatic mappings to BTNT
- coagulation factor X [ATC Code]
gene_encodes_gene_product
- Coagulation Factor Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- F10 Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Complement and Coagulation Cascade [NCIt concept]
- Extrinsic Prothrombin Activation Pathway [NCIt concept]
- Intrinsic Prothrombin Activation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Coagulation Process [NCIt concept]
- Homeostatic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Ligand Binding [NCIt concept]
- Proteolysis [NCIt concept]
- Proteolytic Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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