lipoprotein-associated coagulation inhibitor

Preferred Label : lipoprotein-associated coagulation inhibitor;

MeSH note : MW 38,000; produced by HepG2 hepatoma & other cells; requires factor VII(a), factor X(a) & Ca to express inhibitory activity;

CISMeF synonym : LACI inhibitor; TFI HepG2; TFPI-beta; anticonvertin; antithromboplastin; extrinsic pathway inhibitor I; tissue factor inhibitor, hepatoma; tissue factor pathway inhibitor; xa-dependent factor VIIa-TF inhibitor;

MeSH hyponym : EPI I (extrinsic pathway inhibitor I); TFPIbeta; TFPI;

MeSH Related Number : E1U4X64NFM;

Is substance : O;

Details

Origin ID

C051928;

UMLS CUI

C0065061;

Automatic exact mappings (from CISMeF team)
- TFPI Gene [NCIt concept]
- Tissue Factor Pathway Inhibitor [NCIt concept]
- Tissue factor pathway inhibitor [OMIM gene]
- Tissue factor pathway inhibitor (substance) [SNOMED CT concept]
- tissue factor pathway inhibitor [HGNC gene]
MeSH indexing information
- factor xa [MeSH Descriptor]
MeSH term(s) associated for indexing
- lipoproteins [MeSH Descriptor]
Pharmacological action(s)
- Factor Xa Inhibitors [MeSH Descriptor]
- fibrinolytic agents [MeSH Descriptor]
Record concept(s)
- LACI inhibitor [MeSH concept]
- TFI HepG2 [MeSH concept]
- TFPI-beta [MeSH concept]
- anticonvertin [MeSH concept]
- antithromboplastin [MeSH concept]
- extrinsic pathway inhibitor I [MeSH concept]
- lipoprotein-associated coagulation inhibitor [MeSH concept]
- tissue factor inhibitor, hepatoma [MeSH concept]
- tissue factor pathway inhibitor [MeSH concept]
- xa-dependent factor VIIa-TF inhibitor [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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