Tissue Factor Pathway Inhibitor

Preferred Label : Tissue Factor Pathway Inhibitor;

NCIt synonyms : Lipoprotein-Associated Coagulation Inhibitor; EPI; TFPI; Extrinsic Pathway Inhibitor; LACI;

NCIt definition : Tissue factor pathway inhibitor (304 aa, 35 kDa) is encoded by the human TFPI gene. This protein plays a role in the inhibition of blood coagulation.;

Details

Origin ID

C97262;

UMLS CUI

C4281721;

Automatic exact mappings (from CISMeF team)
- Exocrine pancreatic insufficiency (disorder) [SNOMED CT concept]
- Tissue factor pathway inhibitor [OMIM gene]
- Tissue factor pathway inhibitor (substance) [SNOMED CT concept]
- echo planar [Radlex concept]
- lipoprotein-associated coagulation inhibitor [MeSH Supplementary Concept]
- lipoprotein-associated coagulation inhibitor [MeSH concept]
- tissue factor pathway inhibitor [MeSH concept]
- tissue factor pathway inhibitor [HGNC gene]
OMIM relation
- Tissue factor pathway inhibitor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Inhibitor Gene [NCIt concept]
- Proteinase Inhibitor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- TFPI Gene [NCIt concept]
gene_product_expressed_in_tissue
- Blood [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Acute Myocardial Infarction Pathway [NCIt concept]
- Complement and Coagulation Cascade [NCIt concept]
- Extrinsic Prothrombin Activation Pathway [NCIt concept]
- Syndecan-4-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Enzyme Inhibition [NCIt concept]
- Negative Regulation of Coagulation [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

Main resources

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