" /> Rebimastat - CISMeF





Preferred Label : Rebimastat;

NCIt synonyms : N-((2S)-2-Mercapto-1-oxo-4-(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)butyl)-L-leucyl-N,3-dimethyl-L-valinamide;

NCIt related terms : BMS-275291;

NCIt definition : A sulfhydryl-based second-generation matrix metalloproteinase (MMP) inhibitor with potential antineoplastic activity. Rebimastat selectively inhibits several MMPs (MMP 1, 2, 8, 9, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis.;

Alternative definition : NCI-GLOSS: A substance that is being studied as a treatment for cancer. It belongs to the family of drugs called matrix metalloproteinase inhibitors (MMPIs).;

UNII : 1B47R6ZX4K;

InChIKey : GTXSRFUZSLTDFX-HRCADAONSA-N;

CAS number : 259188-38-0;

Molecule name : BMS-275291; D2163;

Chemical formula : C23H41N5O5S;

NSC code : 713763;

Codes from synonyms : 50521; CDR0000044972; 120714;

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31/07/2025


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