NCIt definition : A small-molecule inhibitor of Aurora kinases A, B and C with potential antineoplastic
activity. Aurora kinase inhibitor AMG 900 selectively binds to and inhibits the activities
of Aurora kinases A, B and C, which may result in inhibition of cellular division
and proliferation in tumor cells that overexpress these kinases. Aurora kinases are
serine-threonine kinases that play essential roles in mitotic checkpoint control during
mitosis and are overexpressed by a wide variety of cancer cell types.;
UNII : 9R2G075611;
CAS number : 945595-80-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 945595-80-2
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