" /> Chloroquinoxaline Sulfonamide - CISMeF





Preferred Label : Chloroquinoxaline Sulfonamide;

NCIt synonyms : chlorosulfaquinoxaline; Chlorsulfaquinoxaline; Benzenesulfonamide, 4-amino-N-(5-chloro-2-quinoxalinyl)-;

NCIt related terms : Benzenesulfonamide, 4-amino-N-[5-chloro-2-quinoxalinyl]-; CQS;

NCIt definition : A chlorinated heterocyclic sulfanilamide with potential antineoplastic activity and potential immunosuppressive activity. Chloroquinoxaline sulfonamide poisons topoisomerase II alpha and topoisomerase II beta, thereby causing double-stranded breaks in DNA, accumulation of unrepaired DNA, and apoptosis. This agent also exhibits lymphotoxicity by inhibiting lymphocyte activation in a cell cycle-specific manner. (NCI04);

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of cancer. It is a type of topoisomerase inhibitor.;

UNII : O0408QB48D;

CAS number : 97919-22-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 97919-22-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

NSC code : 339004;

Codes from synonyms : CDR0000044381; NSC0339004; CDR0000045331;

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14/05/2024


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