NCIt related terms : Benzenesulfonamide, 4-amino-N-[5-chloro-2-quinoxalinyl]-; CQS;
NCIt definition : A chlorinated heterocyclic sulfanilamide with potential antineoplastic activity and
potential immunosuppressive activity. Chloroquinoxaline sulfonamide poisons topoisomerase
II alpha and topoisomerase II beta, thereby causing double-stranded breaks in DNA,
accumulation of unrepaired DNA, and apoptosis. This agent also exhibits lymphotoxicity
by inhibiting lymphocyte activation in a cell cycle-specific manner. (NCI04);
Alternative definition : NCI-GLOSS: A substance being studied in the treatment of cancer. It is a type of topoisomerase
inhibitor.;
UNII : O0408QB48D;
CAS number : 97919-22-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 97919-22-7
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G-SRS /a ;
NSC code : 339004;
Codes from synonyms : CDR0000044381; NSC0339004; CDR0000045331;