DNA Repair Inhibition

Preferred Label : DNA Repair Inhibition;

NCIt definition : DNA Repair Inhibition involves interference with, or restraint of, the enzymatic restoration of a continuous two-stranded DNA molecule without mismatch from a molecule that contains regions damaged by chemical or radiation exposure or by spontaneous damage.;

Details

Origin ID

C40661;

UMLS CUI

C1511688;

Automatic exact mappings (from CISMeF team)
- negative regulation of DNA repair [GO term]
Semantic type(s)
- Genetic Function [UMLS semantic type]
biological_process_involves_gene_product
- Ubiquitin Carboxyl-Terminal Hydrolase 1 [NCIt concept]
biological_process_is_part_of_process
- Cell Survival [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- Chloroquinoxaline Sulfonamide [NCIt concept]
- Hydroxyurea [NCIt concept]
- Idronoxil Suppository NOX66 [NCIt concept]
- O6-Benzylguanine [NCIt concept]
- Topoisomerase-II Inhibitor Racemic XK469 [NCIt concept]
process_involves_gene
- USP1 Gene [NCIt concept]
- USP1 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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