Dentin Sialophosphoprotein

Preferred Label : Dentin Sialophosphoprotein;

NCIt synonyms : DSPP;

NCIt definition : Dentin sialophosphoprotein (1301 aa, 131 kDa) is encoded by the human DSPP gene. This protein plays a role in the formation of dentin and in tooth mineralization.;

NCIt note : Dentin sialophosphoprotein is a precursor that is cleaved to yield dentin sialoprotein (DSP) and dentin phosphoprotein (DPP, or phosphophoryn), which are the two principal noncollagenous proteins in mature dentin matrices.;

Details

Origin ID

C200900;

OMIM relation
- Dentin sialophosphoprotein [OMIM gene]
gene_encodes_gene_product
- DSPP Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Ameloblast [NCIt concept]
- Dentin [NCIt concept]
- Extracellular Matrix [NCIt concept]
- Odontoblast [NCIt concept]
gene_product_is_element_in_pathway
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Mineralization [NCIt concept]
- Morphogenesis [NCIt concept]
- Odontogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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