Mucin-4 - CISMeF

Preferred Label : Mucin-4;

NCIt synonyms : Tracheobronchial Mucin; Ascites Sialoglycoprotein; Testis Mucin; MUC-4; Pancreatic Adenocarcinoma Mucin; MUC4;

NCIt definition : Mucin-4 (2169 aa, 232 kDa) is encoded by the human MUC4 gene. This protein is involved in receptor signaling, the modulation of cell-matrix adhesion, and in tumor progression.;

NCIt note : Mucin-4 is proteolytically cleaved into 2 chains: mucin-4 alpha chain (ascites sialoglycoprotein 1; ASGP-1) and mucin-4 beta chain (ascites sialoglycoprotein 2; ASGP-2). (UniProt);

Details

Origin ID

C128856;

UMLS CUI

C1744064;

OMIM relation
- Mucin 4, tracheobronchial [OMIM gene]
See also inter- (CISMeF)
- Mucin 4, tracheobronchial [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MUC4 protein, human [MeSH Supplementary Concept]
- MUC4 protein, human [MeSH concept]
Validated automatic mappings to NTBT
- Mucin-4 [MeSH Descriptor]
- Mucin-4 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- MUC4 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epithelial Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
- Mucus [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell-Matrix Adhesion Process [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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