" /> A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13 - CISMeF





Preferred Label : A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13;

NCIt synonyms : EC 3.4.24.87; A Disintegrin and Metalloprotease with Thrombospondin Motifs-13; vWF-CP; vWF-Cleaving Protease; ADAM-TS13; ADAMTS-13; ADAM-TS 13;

NCIt related terms : ADAMTS13; ADAM Metallopeptidase With Thrombospondin Type 1 Motif 13; A Disintegrin and Metalloproteinase with Thrombospondin Type 1 Motif 13; Von Willebrand Coagulation Factor Cleaving Protease;

NCIt definition : A disintegrin and metalloproteinase with thrombospondin motifs 13 (1427 aa, 154 kDa) is encoded by the human ADAMTS13 gene. This protein plays a role in the proteolysis of von Willebrand factor multimers.;

Alternative definition : CDISC: An antigen encoded by the ADAMTS13 gene and cleaves von Willebrand Factor (vWF). It can be considered as an autoantigen and is commonly associated with the autoimmune disease immune-mediated thrombotic thrombocytopenic purpura (iTTP).;

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11/05/2025


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