A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13

Preferred Label : A Disintegrin and Metalloproteinase with Thrombospondin Motifs 13;

NCIt synonyms : EC 3.4.24.87; A Disintegrin and Metalloprotease with Thrombospondin Motifs-13; vWF-CP; vWF-Cleaving Protease; ADAM-TS13; ADAMTS-13; ADAM-TS 13; ADAMTS13;

NCIt definition : A disintegrin and metalloproteinase with thrombospondin motifs 13 (1427 aa, 154 kDa) is encoded by the human ADAMTS13 gene. This protein plays a role in the proteolysis of von Willebrand factor multimers.;

Details

Origin ID

C118327;

UMLS CUI

C0389918;

Automatic exact mappings (from CISMeF team)
- A disintegrin-like and metalloprotease with thrombospondin type 1 motif, 13 [OMIM gene]
- ADAM metallopeptidase with thrombospondin type 1 motif 13 [ORDO Gene]
- ADAMTS13 Protein [MeSH Descriptor]
OMIM relation
- A disintegrin-like and metalloprotease with thrombospondin type 1 motif, 13 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ADAMTS13 protein, human [MeSH Supplementary Concept]
- ADAMTS13 protein, human [MeSH concept]
- von Willebrand factor (vWf) cleaving protease [LOINC component]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ADAMTS13 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
- Peptidase Family M12B [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Disintegrin Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Coagulation Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Integrin Binding [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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