Canstatin - CISMeF

Preferred Label : Canstatin;

NCIt synonyms : COL4A2 C-Terminal NC1 Peptide; Collagen Alpha-2(IV) Chain C-Terminal NC1 Peptide;

NCIt definition : Canstatin (227 aa, 25 kDa) is encoded by the human COL4A2 gene. This protein plays a role in the inhibition of angiogenesis.;

NCIt note : Canstatin is a cleavage product consisting of the the C-terminal NC1 of collagen alpha-2(IV) chain. (UniProt);

NCI Metathesaurus CUI : CL554188;

Details

Origin ID

C152985;

UMLS CUI

C4723814;

Automatic exact mappings (from CISMeF team)
- collagen type IV alpha 2 chain [ORDO Gene]
- collagen type IV alpha 2 chain [HGNC gene]
OMIM relation
- Collagen, type iv, alpha-2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- COL4A2 Gene [NCIt concept]
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Matrix [NCIt concept]
gene_product_has_biochemical_function
- Angiogenesis Inhibitory Protein [NCIt concept]
gene_product_has_chemical_classification
- Protein Fragment [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Inhibition of Cell Proliferation [NCIt concept]
- Morphogenesis [NCIt concept]
- Negative Regulation of Angiogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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