Collagen Alpha-5(IV) Chain

Preferred Label : Collagen Alpha-5(IV) Chain;

NCIt synonyms : Collagen IV (Alpha 5); Collagen IV Alpha-5 Chain; COL4A5;

NCIt definition : Collagen alpha-5(IV) chain (1685 aa, 161 kDa) is encoded by the human COL4A5 gene. This protein is involved in the structure of the extracellular matrix.;

NCIt note : Collagen alpha-5(IV) chain is an isoform of a type IV collagen alpha chain, which can form a triple helix structure with two other chains to form a network composed of type IV collagen. Type IV collagen is the most abundant structural component of the extracellular matrix. (SwissProt);

Details

Origin ID

C71451;

UMLS CUI

C2347825;

OMIM relation
- Collagen, type iv, alpha-5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- COL4A5 Gene [NCIt concept]
- Collagen Gene [NCIt concept]
- Extracellular Matrix Protein Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Basement Membrane [NCIt concept]
- Extracellular Matrix [NCIt concept]
gene_product_has_biochemical_function
- Collagen [NCIt concept]
gene_product_has_chemical_classification
- Extracellular Matrix Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_physical_part_of
- Collagen IV [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Movement [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Morphogenesis [NCIt concept]
- Organogenesis [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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