" /> Basement Membrane-Specific Heparan Sulfate Proteoglycan Core Protein - CISMeF





Preferred Label : Basement Membrane-Specific Heparan Sulfate Proteoglycan Core Protein;

NCIt synonyms : Perlecan; HSPG; PLC;

NCIt definition : Basement membrane-specific heparan sulfate proteoglycan core protein (4391 aa, 469 kDa) is encoded by the human HSPG2 gene. This protein is involved in both the mediation of cell adhesion and the structural integrity of the basement membrane.;

NCIt note : Proteolytic processing of basement membrane-specific heparan sulfate proteoglycan core protein produces the C-terminal peptide, endorepellin. This peptide can be further processed to produce the LG3 peptide. Both peptides inhibit angiogenesis. (UniProt);

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30/07/2025


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