Calpain-3 - CISMeF

Preferred Label : Calpain-3;

NCIt synonyms : Calcium-Activated Neutral Proteinase 3; Calpain p94; CANP 3; New Calpain 1; EC 3.4.22.54; Calpain 3; CAPN3; nCL-1; Calpain L3; Muscle-Specific Calcium-Activated Neutral Protease 3;

NCIt definition : Calpain-3 (821 aa, 94 kDa) is encoded by the human CAPN3 gene. This protein plays a role in cysteine proteinase activity against a variety of protein substrates.;

Details

Origin ID

C192749;

UMLS CUI

C1384580;

OMIM relation
- Calpain 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CAPN3 protein, human [MeSH Supplementary Concept]
- CAPN3 protein, human [MeSH concept]
gene_encodes_gene_product
- CAPN3 Gene [NCIt concept]
- Cysteine Peptidase Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Skeletal Muscle Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Calpain [NCIt concept]
gene_product_has_structural_domain_or_motif
- EF-Hand Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Protein Cleavage [NCIt concept]
- Protein Degradation Process [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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