Protein Degradation Process

Preferred Label : Protein Degradation Process;

NCIt synonyms : Protein Degradation; Protein Degradation, Regulatory;

NCIt definition : Specific degradation of a protein - involving conjugation, transport, oxidation, and proteolysis - involved in signal transduction or cell communication events; not to be confuse with proteolysis, which applies only to peptide bond hydrolysis. (NCI);

Details

Origin ID

C18104;

UMLS CUI

C1623036;

Automatic exact mappings (from CISMeF team)
- proteolysis [Artificial nutrition thesaurus concept]
Currated CISMeF NLP mapping
- protein catabolic process [GO term]
- protein degradation [Disease (Nov.)]
- proteolysis [MeSH Descriptor]
See also inter- (CISMeF)
- proteolysis [MeSH concept]
Semantic type(s)
- Molecular Function [UMLS semantic type]
UMLS correspondences (same concept)
- protein catabolic process [GO term]
biological_process_involves_gene_product
- 26S Proteasome Complex Subunit SEM1 [NCIt concept]
- 26S Proteasome Non-ATPase Regulatory Subunit 10 [NCIt concept]
- ATP-Dependent Clp Protease Proteolytic Subunit, Mitochondrial [NCIt concept]
- Calpain-3 [NCIt concept]
- Carboxypeptidase A6 [NCIt concept]
- Chymotrypsin-Like Elastase Family Member 1 [NCIt concept]
- Cullin Family Protein [NCIt concept]
- Cullin-1 [NCIt concept]
- Cullin-2 [NCIt concept]
- Cullin-3 [NCIt concept]
- Cullin-4A [NCIt concept]
- Cullin-4B [NCIt concept]
- Cullin-5 [NCIt concept]
- DDB1- and CUL4-Associated Factor 1 [NCIt concept]
- E3 Ubiquitin-Protein Ligase MDM2 [NCIt concept]
- Elongin-C [NCIt concept]
- Lon Protease Homolog, Mitochondrial [NCIt concept]
- Matrix Metalloproteinase-9 [NCIt concept]
- Pancreatic Elastase [NCIt concept]
- Polyubiquitin-B [NCIt concept]
- Polyubiquitin-C [NCIt concept]
- Proteasome Subunit Alpha Type-5 [NCIt concept]
- Ras-Related Protein Rab-12 [NCIt concept]
- Ras-Related Protein Rab-7a [NCIt concept]
- Ubiquilin-4 [NCIt concept]
- Ubiquitin [NCIt concept]
- Ubiquitin D [NCIt concept]
- Xaa-Pro Dipeptidase [NCIt concept]
biological_process_is_part_of_process
- Biochemical Process [NCIt concept]
process_includes_biological_process
- Monoubiquitination [NCIt concept]
- Polyubiquitination [NCIt concept]
- Ubiquitination [NCIt concept]
process_involves_gene
- CAPN3 Gene [NCIt concept]
- CAPN3 wt Allele [NCIt concept]
- CLPP Gene [NCIt concept]
- CLPP wt Allele [NCIt concept]
- CPA6 Gene [NCIt concept]
- CPA6 wt Allele [NCIt concept]
- CUL1 Gene [NCIt concept]
- CUL1 wt Allele [NCIt concept]
- CUL2 Gene [NCIt concept]
- CUL2 wt Allele [NCIt concept]
- CUL3 Gene [NCIt concept]
- CUL3 wt Allele [NCIt concept]
- CUL4A Gene [NCIt concept]
- CUL4A wt Allele [NCIt concept]
- CUL4B Gene [NCIt concept]
- CUL4B wt Allele [NCIt concept]
- CUL5 Gene [NCIt concept]
- CUL5 wt Allele [NCIt concept]
- Cullin Family Gene [NCIt concept]
- DCAF1 Gene [NCIt concept]
- DCAF1 wt Allele [NCIt concept]
- ELOC Gene [NCIt concept]
- ELOC wt Allele [NCIt concept]
- FEM1C Gene [NCIt concept]
- FEM1C wt Allele [NCIt concept]
- KLK6 Gene [NCIt concept]
- KLK6 wt Allele [NCIt concept]
- LONP1 Gene [NCIt concept]
- LONP1 wt Allele [NCIt concept]
- MDM2 Gene [NCIt concept]
- MDM2 SNP309 Allele [NCIt concept]
- MDM2 wt Allele [NCIt concept]
- MMP9 Gene [NCIt concept]
- MMP9 wt Allele [NCIt concept]
- PEPD Gene [NCIt concept]
- PEPD wt Allele [NCIt concept]
- PSMA5 Gene [NCIt concept]
- PSMA5 wt Allele [NCIt concept]
- PSMB10 Gene [NCIt concept]
- PSMB10 wt Allele [NCIt concept]
- PSMB5 Gene [NCIt concept]
- PSMB5 wt Allele [NCIt concept]
- PSMB8 Gene [NCIt concept]
- PSMB8 wt Allele [NCIt concept]
- PSMB9 Gene [NCIt concept]
- PSMB9 wt Allele [NCIt concept]
- RAB12 Gene [NCIt concept]
- RAB12 wt Allele [NCIt concept]
- RAB7A Gene [NCIt concept]
- RAB7A wt Allele [NCIt concept]
- RNF11 Gene [NCIt concept]
- RNF11 wt Allele [NCIt concept]
- SEM1 Gene [NCIt concept]
- SEM1 wt Allele [NCIt concept]
- UBB Gene [NCIt concept]
- UBB wt Allele [NCIt concept]
- UBC Gene [NCIt concept]
- UBC wt Allele [NCIt concept]
- UBQLN4 Gene [NCIt concept]
- UBQLN4 wt Allele [NCIt concept]

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