Ubiquitin Carboxyl-Terminal Hydrolase 38

Preferred Label : Ubiquitin Carboxyl-Terminal Hydrolase 38;

NCIt synonyms : EC 3.4.19.12; Ubiquitin Specific Protease 38; USP38; Ubiquitin Thioesterase 38; Ubiquitin-Specific Protease 38; Ubiquitin-Specific-Processing Protease 38; Ubiquitin Thiolesterase 38; Ubiquitin Specific Peptidase 38; Deubiquitinating Enzyme 38; HP43.8KD;

NCIt definition : Ubiquitin carboxyl-terminal hydrolase 38 (1042 aa, 117 kDa) is encoded by the human USP38 gene. This protein plays a role in protein deubiquitination.;

NCIt note : Ubiquitin carboxyl-terminal hydrolase 38 is involved in antiviral response by removing Lys-48-linked and Lys-63-linked polyubiquitined chains from Zika virus envelope protein E. (UniProt);

Details

Origin ID

C205767;

OMIM relation
- Ubiquitin-specific protease 38 [OMIM gene]
gene_encodes_gene_product
- Cysteine Peptidase Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
- USP38 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitin C-Terminal Hydrolase [NCIt concept]
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Antiviral Response [NCIt concept]
- Deubiquitination [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Degradation Process [NCIt concept]
- Proteolysis [NCIt concept]
- Regulation of Proteolysis [NCIt concept]

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