Xaa-Pro Dipeptidase

Preferred Label : Xaa-Pro Dipeptidase;

NCIt synonyms : X-Pro Dipeptidase; Prolidase; Proline Dipeptidase; Aminoacyl-L-Proline Hydrolase; Testicular Tissue Protein Li 138; Peptidase D; EC 3.4.13.9; PEPD; Imidodipeptidase;

NCIt definition : Xaa-Pro dipeptidase (493 aa, 54 kDa) is encoded by the human PEPD gene. This protein plays a role in the cleavage of dipeptides with a prolyl or hydroxyprolyl residue in the C-terminal position.;

NCI Metathesaurus CUI : CL964441;

Details

Origin ID

C190599;

UMLS CUI

C4743185;

Automatic exact mappings (from CISMeF team)
- Paroxysmal extreme pain disorder [OMIM Phenotype]
- Peptidase D [OMIM gene]
- Proline dipeptidase [LOINC component]
- Proline dipeptidase (substance) [SNOMED CT concept]
- Prolyl dipeptidase (substance) [SNOMED CT concept]
- paroxysmal extreme pain disorder [DO Concept]
- peptidase D [HGNC gene]
- peptidase D [ORDO Gene]
- proline dipeptidase [MeSH concept]
- proline dipeptidase [SNOMED Notion]
- proline dipeptidase [MeSH Supplementary Concept]
OMIM relation
- Peptidase D [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PEPD protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- PEPD Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Exosome [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Peptide Metabolism [NCIt concept]
- Protein Degradation Process [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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