CUL4A wt Allele

Preferred Label : CUL4A wt Allele;

NCIt synonyms : Cullin 4A wt Allele;

NCIt definition : Human CUL4A wild-type allele is located within 13q34 and is approximately 56 kb in length. This allele, which encodes cullin-4A protein, is plays a role in the ubiquitination and subsequent proteasome-dependent degradation of target proteins. It is also involved in both repair of ultraviolet light-induced DNA damage and the S-phase DNA damage response.;

GenBank Accession Number : NM_003589;

Details

Origin ID

C52065;

UMLS CUI

C1707167;

OMIM relation
- Cullin 4a [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_has_physical_location
- 13: 112912288-112967400 [NCIt concept]
gene_in_chromosomal_location
- 13q34 [NCIt concept]
gene_is_element_in_pathway
- Nucleotide Excision Repair Pathway [NCIt concept]
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_plays_role_in_process
- Protein Degradation Process [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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