Lon Protease Homolog, Mitochondrial

Preferred Label : Lon Protease Homolog, Mitochondrial;

NCIt synonyms : LONP1; LONHs; EC 3.4.21.53; Lon Peptidase 1, Mitochondrial; Lon Protease-Like Protein; hLON ATP-Dependent Protease; LONP; Mitochondrial ATP-Dependent Protease Lon; Mitochondrial Lon Protease-Like Protein;

NCIt definition : Lon protease homolog, mitochondrial (959 aa, 106 kDa) is encoded by the human LONP1 gene. This protein is involved in the selective degradation of misfolded or damaged polypeptides and of short-lived regulatory proteins.;

Détails

Origin ID

C202942;

UMLS CUI

C4042433;

OMIM relation
- Lon peptidase 1, mitochondrial [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- LONP1 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- LONP1 Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Mitochondrial Matrix [NCIt concept]
- Nucleoplasm [NCIt concept]
gene_product_has_biochemical_function
- RNA Binding Protein [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- DNA Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Degradation Process [NCIt concept]
- Proteolysis [NCIt concept]
- RNA Binding [NCIt concept]
- Unfolded Protein Response [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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