Unfolded Protein Response

Preferred Label : Unfolded Protein Response;

NCIt synonyms : UPR; Cellular Response to Unfolded Protein;

NCIt definition : A cellular stress response process that is activated by the accumulation of unfolded or misfolded proteins in the cell.;

Details

Origin ID

C118900;

UMLS CUI

C1155342;

Automatic exact mappings (from CISMeF team)
- cellular response to unfolded protein [GO term]
- response to unfolded protein [GO term]
- unfolded protein response [MeSH Descriptor]
- unfolded protein response [MeSH concept]
Semantic type(s)
- Cell Function [UMLS semantic type]
UMLS correspondences (same concept)
- cellular response to unfolded protein [GO term]
- unfolded protein response [MeSH Descriptor]
- unfolded protein response [MeSH concept]
biological_process_involves_gene_product
- 60 kDa Heat Shock Protein, Mitochondrial [NCIt concept]
- 78 kDa Glucose-Regulated Protein [NCIt concept]
- Alpha-2-Macroglobulin Receptor-Associated Protein [NCIt concept]
- Ataxin-3 [NCIt concept]
- Auxilin [NCIt concept]
- B-Cell Receptor-Associated Protein 31 [NCIt concept]
- C1GALT1-Specific Chaperone 1 [NCIt concept]
- Calnexin [NCIt concept]
- Chaperone [NCIt concept]
- Derlin-1 [NCIt concept]
- DnaJ Homolog Subfamily A Member 1 [NCIt concept]
- DnaJ Homolog Subfamily B Member 1 [NCIt concept]
- DnaJ Homolog Subfamily B Member 4 [NCIt concept]
- DnaJ Homolog Subfamily B Member 6 [NCIt concept]
- DnaJ Homolog Subfamily C Member 12 [NCIt concept]
- DnaJ Homolog Subfamily C Member 5 [NCIt concept]
- E3 Ubiquitin-Protein Ligase CHIP [NCIt concept]
- E3 Ubiquitin-Protein Ligase RNF5 [NCIt concept]
- Endoplasmin [NCIt concept]
- FAS-Associated Factor 2 [NCIt concept]
- Heat Shock 70 kDa Protein 1A/1B [NCIt concept]
- Heat Shock 70 kDa Protein 4L [NCIt concept]
- Heat Shock Factor Protein 1 [NCIt concept]
- Heat Shock Protein 105 kDa [NCIt concept]
- Heat Shock Protein 75 kDa, Mitochondrial [NCIt concept]
- Heat Shock Protein Beta-1 [NCIt concept]
- Heat Shock Protein Beta-8 [NCIt concept]
- Heat Shock Protein HSP 90-Alpha [NCIt concept]
- Heat Shock Protein HSP 90-Beta [NCIt concept]
- Hsp90 Co-Chaperone CDC37 [NCIt concept]
- LDLR Chaperone MESD [NCIt concept]
- Lipase Maturation Factor 1 [NCIt concept]
- Lon Protease Homolog, Mitochondrial [NCIt concept]
- Membrane-Bound Transcription Factor Site-2 Protease [NCIt concept]
- Mitochondrial Import Inner Membrane Translocase Subunit TIM14 [NCIt concept]
- Peptide-N(4)-(N-Acetyl-Beta-Glucosaminyl)Asparagine Amidase [NCIt concept]
- Peroxisome Assembly Protein 12 [NCIt concept]
- Peroxisome Biogenesis Factor 10 [NCIt concept]
- Peroxisome Biogenesis Factor 2 [NCIt concept]
- Proteasome Assembly Chaperone 2 [NCIt concept]
- Protein Unc-45 Homolog A [NCIt concept]
- Putative Endoplasmin-Like Protein [NCIt concept]
- Sacsin [NCIt concept]
- Serum Amyloid P-Component [NCIt concept]
- Small Glutamine-Rich Tetratricopeptide Repeat-Containing Protein Alpha [NCIt concept]
- Torsin-1A [NCIt concept]
- Tubulin-Specific Chaperone Cofactor E-Like Protein [NCIt concept]
- Tubulin-Specific Chaperone E [NCIt concept]
- UDP-Glucose:Glycoprotein Glucosyltransferase 2 [NCIt concept]
- Vesicle-Associated Membrane Protein-Associated Protein B [NCIt concept]
- Vesicle-Associated Membrane Protein-Associated Protein C [NCIt concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
process_involves_gene
- APCS Gene [NCIt concept]
- APCS wt Allele [NCIt concept]
- ATXN3 Gene [NCIt concept]
- ATXN3 wt Allele [NCIt concept]
- BCAP31 Gene [NCIt concept]
- BCAP31 wt Allele [NCIt concept]
- C1GALT1C1 Gene [NCIt concept]
- C1GALT1C1 wt Allele [NCIt concept]
- CANX Gene [NCIt concept]
- CANX wt Allele [NCIt concept]
- CDC37 Gene [NCIt concept]
- CDC37 wt Allele [NCIt concept]
- Chaperone Protein Gene [NCIt concept]
- DERL1 Gene [NCIt concept]
- DERL1 wt Allele [NCIt concept]
- DNAJA1 Gene [NCIt concept]
- DNAJA1 wt Allele [NCIt concept]
- DNAJB1 Gene [NCIt concept]
- DNAJB1 wt Allele [NCIt concept]
- DNAJB4 Gene [NCIt concept]
- DNAJB4 wt Allele [NCIt concept]
- DNAJB6 Gene [NCIt concept]
- DNAJB6 wt Allele [NCIt concept]
- DNAJC12 Gene [NCIt concept]
- DNAJC12 wt Allele [NCIt concept]
- DNAJC19 Gene [NCIt concept]
- DNAJC19 wt Allele [NCIt concept]
- DNAJC5 Gene [NCIt concept]
- DNAJC5 wt Allele [NCIt concept]
- DNAJC6 Gene [NCIt concept]
- DNAJC6 wt Allele [NCIt concept]
- FAF2 Gene [NCIt concept]
- FAF2 wt Allele [NCIt concept]
- HSF1 Gene [NCIt concept]
- HSF1 wt Allele [NCIt concept]
- HSP90AA1 Gene [NCIt concept]
- HSP90AA1 wt Allele [NCIt concept]
- HSP90AB1 Gene [NCIt concept]
- HSP90AB1 wt Allele [NCIt concept]
- HSP90B1 Gene [NCIt concept]
- HSP90B1 wt Allele [NCIt concept]
- HSP90B2P Gene [NCIt concept]
- HSP90B2P wt Allele [NCIt concept]
- HSPA1A Gene [NCIt concept]
- HSPA1A wt Allele [NCIt concept]
- HSPA1B Gene [NCIt concept]
- HSPA1B wt Allele [NCIt concept]
- HSPA4L Gene [NCIt concept]
- HSPA4L wt Allele [NCIt concept]
- HSPA5 Gene [NCIt concept]
- HSPA5 wt Allele [NCIt concept]
- HSPB1 Gene [NCIt concept]
- HSPB1 wt Allele [NCIt concept]
- HSPB8 Gene [NCIt concept]
- HSPB8 wt Allele [NCIt concept]
- HSPD1 Gene [NCIt concept]
- HSPD1 wt Allele [NCIt concept]
- HSPH1 Gene [NCIt concept]
- HSPH1 wt Allele [NCIt concept]
- LMF1 Gene [NCIt concept]
- LMF1 wt Allele [NCIt concept]
- LONP1 Gene [NCIt concept]
- LONP1 wt Allele [NCIt concept]
- LRPAP1 Gene [NCIt concept]
- LRPAP1 wt Allele [NCIt concept]
- MBTPS2 Gene [NCIt concept]
- MBTPS2 wt Allele [NCIt concept]
- MESD Gene [NCIt concept]
- MESD wt Allele [NCIt concept]
- NGLY1 Gene [NCIt concept]
- NGLY1 wt Allele [NCIt concept]
- PEX10 Gene [NCIt concept]
- PEX10 wt Allele [NCIt concept]
- PEX12 Gene [NCIt concept]
- PEX12 wt Allele [NCIt concept]
- PEX2 Gene [NCIt concept]
- PEX2 wt Allele [NCIt concept]
- PSMG2 Gene [NCIt concept]
- PSMG2 wt Allele [NCIt concept]
- RNF5 Gene [NCIt concept]
- RNF5 wt Allele [NCIt concept]
- SACS Gene [NCIt concept]
- SACS wt Allele [NCIt concept]
- SGTA Gene [NCIt concept]
- SGTA wt Allele [NCIt concept]
- STUB1 Gene [NCIt concept]
- STUB1 wt Allele [NCIt concept]
- TBCE Gene [NCIt concept]
- TBCE wt Allele [NCIt concept]
- TBCEL Gene [NCIt concept]
- TBCEL wt Allele [NCIt concept]
- TOR1A Gene [NCIt concept]
- TOR1A wt Allele [NCIt concept]
- TRAP1 Gene [NCIt concept]
- TRAP1 wt Allele [NCIt concept]
- UGGT2 Gene [NCIt concept]
- UGGT2 wt Allele [NCIt concept]
- UNC45A Gene [NCIt concept]
- UNC45A wt Allele [NCIt concept]
- VAPB Gene [NCIt concept]
- VAPB wt Allele [NCIt concept]

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