DNAJB4 wt Allele

Preferred Label : DNAJB4 wt Allele;

NCIt synonyms : DnaJ Homolog Subfamily B Member 4 wt Allele; HLJ1; DjB4; DNAJW;

NCIt definition : Human DNAJB4 wild-type allele is located in the vicinity of 1p31.1 and is approximately 12 kb in length. This allele, which encodes DnaJ homolog subfamily B member 4 protein, plays a role in the regulation of protein chaperone activity. The expression of the allele correlates negatively with cancer cell invasion ability. Further, it has been demonstrated to have an inhibitory effect on non-small-cell lung cancer development and is currently being investigated as a prognostic biomarker for the disease.;

GenBank Accession Number : NM_007034;

Details

Origin ID

C62455;

UMLS CUI

C1880238;

OMIM relation
- Dnaj/hsp40 homolog, subfamily b, member 4 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 1p31 [NCIt concept]
gene_plays_role_in_process
- Cellular Stress Response [NCIt concept]
- Protein Folding [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Unfolded Protein Response [NCIt concept]

Keyword's position in hierarchy(ies) :

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