Wolframin - CISMeF

Preferred Label : Wolframin;

NCIt synonyms : Wolframin ER Transmembrane Glycoprotein; WFS1;

NCIt definition : Wolframin (890 aa, 100 kDa) is encoded by the human WFS1 gene. This protein plays a role in the modulation of endoplasmic reticulum stress responses.;

NCIt note : Wolframin may be a novel ER calcium channel. (J Biol Chem. 2003; 278:52755-62. doi: 10.1074/jbc.M310331200.);

PubMed : 14527944;

Détails

Origin ID

C213581;

OMIM relation
- Wolframin er transmembrane glycoprotein [OMIM gene]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
- WFS1 Gene [NCIt concept]
gene_product_expressed_in_tissue
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Homeostasis [NCIt concept]
- Hearing [NCIt concept]
- Ligand Binding [NCIt concept]
- Negative Regulation of Apoptosis [NCIt concept]
- Sight [NCIt concept]
- Transport Process [NCIt concept]
- Unfolded Protein Response [NCIt concept]

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