Derlin-1 - CISMeF

Preferred Label : Derlin-1;

NCIt synonyms : Derlin 1; DERL1; Der1-Like Protein 1; DERtrin-1; Degradation in Endoplasmic Reticulum Protein 1;

NCIt definition : Derlin-1 (251 aa, 29 kDa) is encoded by the human DERL1 gene. This protein plays a role in recognition and transport of misfolded proteins out of the endoplasmic reticulum.;

Details

Origin ID

C201240;

UMLS CUI

C1453791;

OMIM relation
- Der1-like domain family, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- DERL1 protein, human [MeSH Supplementary Concept]
- DERL1 protein, human [MeSH concept]
gene_encodes_gene_product
- DERL1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amyotrophic Lateral Sclerosis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Protein Degradation Induction [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]
- Unfolded Protein Response [NCIt concept]

Keyword's position in hierarchy(ies) :

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