Protein Degradation Induction

Preferred Label : Protein Degradation Induction;

NCIt definition : Protein Degradation Induction involves initiation of specific degradation of a protein - involving conjugation, transport, oxidation, and proteolysis. Often involved in signal transduction or cell communication events, protein degradation is not to be confused with proteolysis, which applies only to peptide bond hydrolysis. (NCI);

Details

Origin ID

C40673;

UMLS CUI

C1514540;

Semantic type(s)
- Physiologic Function [UMLS semantic type]
biological_process_involves_gene_product
- Chymotrypsin-C [NCIt concept]
- Chymotrypsinogen B [NCIt concept]
- Chymotrypsinogen B2 [NCIt concept]
- Derlin-1 [NCIt concept]
- E3 Ubiquitin-Protein Ligase HUWE1 [NCIt concept]
- Trypsin-1 [NCIt concept]
- Trypsin-2 [NCIt concept]
- Ubiquitin-Conjugating Enzyme E2 L3 [NCIt concept]
biological_process_is_part_of_process
- Biochemical Process [NCIt concept]
is_physiologic_effect_of_chemical_or_drug
- Alvespimycin [NCIt concept]
- Alvespimycin Hydrochloride [NCIt concept]
- Geldanamycin Analogue [NCIt concept]
- Herbimycin [NCIt concept]
- Hsp90 Inhibitor BIIB021 [NCIt concept]
- Retaspimycin [NCIt concept]
- Retaspimycin Hydrochloride [NCIt concept]
- Tanespimycin [NCIt concept]
process_involves_gene
- CTRB1 Gene [NCIt concept]
- CTRB1 wt Allele [NCIt concept]
- CTRB2 Gene [NCIt concept]
- CTRB2 wt Allele [NCIt concept]
- CTRC Gene [NCIt concept]
- CTRC wt Allele [NCIt concept]
- DERL1 Gene [NCIt concept]
- DERL1 wt Allele [NCIt concept]
- HUWE1 Gene [NCIt concept]
- HUWE1 wt Allele [NCIt concept]
- PRSS1 Gene [NCIt concept]
- PRSS1 wt Allele [NCIt concept]
- PRSS2 Gene [NCIt concept]
- PRSS2 wt Allele [NCIt concept]
- UBE2L3 Gene [NCIt concept]
- UBE2L3 wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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