Hepcidin-25 - CISMeF

Preferred Label : Hepcidin-25;

NCIt synonyms : Hepc25; HAMP;

NCIt definition : Hepcidin-25 (25 aa, 3 kDa) is encoded by the human HAMP gene. This protein plays a role in the regulation of iron hemostasis through binding to and promoting the degradation of the iron transport protein ferroportin (SLC40A1).;

NCIt note : Hepcidin-25 is comprised of amino acid residues 60-84, which are the last 25 carboxyl-terminal residues of full length hepcidin.;

Details

Origin ID

C218850;

OMIM relation
- Hepcidin antimicrobial peptide [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HAMP Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_plays_role_in_biological_process
- Homeostatic Process [NCIt concept]
- Protein Degradation Induction [NCIt concept]
- Protein-Protein Interaction [NCIt concept]

Keyword's position in hierarchy(ies) :

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