HUWE1 Gene - CISMeF

Preferred Label : HUWE1 Gene;

NCIt synonyms : HECT, UBA and WWE Domain Containing E3 Ubiquitin Protein Ligase 1 Gene;

NCIt related terms : HUWE1;

NCIt definition : This gene is involved in the ubiquitination and subsequent proteasomal degradation of induced myeloid leukemia cell differentiation protein Mcl-1, cellular tumor antigen p53, core histone proteins and DNA polymerase beta.;

Details

Origin ID

C181819;

UMLS CUI

C1537395;

HGNC gene
- HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 [HGNC gene]
OMIM relation
- Hect, uba, and wwe domains-containing protein 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 [HGNC gene]
- Hect, uba, and wwe domains-containing protein 1 [OMIM gene]
gene_encodes_gene_product
- E3 Ubiquitin-Protein Ligase HUWE1 [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_plays_role_in_process
- Apoptosis [NCIt concept]
- DNA Repair [NCIt concept]
- Protein Degradation Induction [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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