Preferred Label : Apoptosis;
NCIt synonyms : Programmed Cell Death; Apoptotic Process; PCD;
NCIt definition : A form of programmed cell death that begins when a cell receives internal or external
signals, then proceeds through a series of characteristic stages typically including
rounding-up of the cell, retraction of pseudopods, reduction of cellular volume (pyknosis),
chromatin condensation, nuclear fragmentation (karyorrhexis), and plasma membrane
blebbing, and ends with the death of the cell.;
Alternative definition : NCI-GLOSS: A type of cell death in which a series of molecular steps in a cell leads
to its death. This is the body's normal way of getting rid of unneeded or abnormal
cells. The process of programmed cell death may be blocked in cancer cells.; CDISC: A form of programmed cell death triggered by internal or external signals that
results in a series of characteristic morphological changes.;
NCIt note : Important in ontogenesis, tumorigenesis, tissue turnover, lymphocyte selection and
function and hormone-induced atrophy.;
Codes from synonyms : CDR0000046524; CDR0000407582;
Origin ID : C17557;
UMLS CUI : C0162638;
Automatic exact mappings (from CISMeF team)
- CISMeF manual mappings
- Currated CISMeF NLP mapping
- False automatic mappings
- See also inter- (CISMeF)
- Semantic type(s)
- UMLS correspondences (same concept)
- biological_process_has_associated_location
- biological_process_has_initiator_process
- biological_process_has_result_biological_process
- biological_process_involves_gene_product
- biological_process_is_part_of_process
- biological_process_results_from_biological_process
- concept_is_in_subset
- is_physiologic_effect_of_chemical_or_drug
- process_involves_gene
