" /> BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like - CISMeF





Preferred Label : BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like;

NCIt synonyms : NIX; BNIP3a; NIP3-Like Protein X; BNIP3L; NIP3L; BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3A; Adenovirus E1b19k-Binding Protein B5; BCL2/Adenovirus E1B 19kd Interacting Protein 3-Like; BCL2/Adenovirus E1B 19-Kd Protein-Interacting Protein 3a; Adenovirus E1b19kD-Binding Protein-B5;

NCIt definition : BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (219 aa, 24 kDa) is encoded by the human BNIP3L gene. This protein is involved in the induction of apoptosis.;

NCIt note : BCL2/Adenovirus E1B 19kd Interacting Protein 3-Like, encoded by the BNIP3L gene, is a member of the BCL2/adenovirus E1B 19 kD-interacting protein (BNIP) family. It promotes apoptosis by interacting with the antiapoptotic E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as cellular antiapoptotic proteins Bcl2 and Bcl2L1. It can overcome the suppressor bcl-2 and bcl-xl, although high levels of bcl-xl expression will inhibit apoptosis. This protein is a functional homolog of BNIP3, a proapoptotic protein, and may function simultaneously with BNIP3. It may play a role in tumor suppression. (From LocusLink);

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18/05/2024


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