BCL-2 Family Protein

Preferred Label : BCL-2 Family Protein;

NCIt synonyms : BCL-2 Family; BCL-2 Family Proteins; BCL2 Family; BCL2 Family Protein;

NCIt definition : A family of proteins that all contain at least one of four Bcl-2 homology domains (BH). These proteins are involved in the regulation of apoptosis.;

NCI Metathesaurus CUI : CL554367;

Details

Origin ID

C153109;

UMLS CUI

C4727027;

Automatic exact mappings (from CISMeF team)
- Proto-Oncogene proteins c-bcl-2 [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- BCL-2 Gene Family [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Regulator [NCIt concept]
gene_product_has_structural_domain_or_motif
- Bcl-2 Homology Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
is_chemical_classification_of_gene_product
- Activator of Apoptosis Harakiri [NCIt concept]
- Apoptosis Regulator BAX [NCIt concept]
- Apoptosis Regulator Bcl-2 [NCIt concept]
- BCL2-Related Protein A1 [NCIt concept]
- BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3 [NCIt concept]
- BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3-Like [NCIt concept]
- BH3-Interacting Domain Death Agonist [NCIt concept]
- Bcl-2 Homologous Antagonist/Killer [NCIt concept]
- Bcl-2-Interacting Killer [NCIt concept]
- Bcl-2-Like Protein 1 [NCIt concept]
- Bcl-2-Like Protein 10 [NCIt concept]
- Bcl-2-Like Protein 11 [NCIt concept]
- Bcl-2-Like Protein 12 [NCIt concept]
- Bcl-2-Like Protein 2 [NCIt concept]
- Bcl-2-Modifying Factor [NCIt concept]
- Bcl-2-Related Ovarian Killer Protein [NCIt concept]
- Bcl-X(S) [NCIt concept]
- Bcl2 Antagonist of Cell Death [NCIt concept]
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 [NCIt concept]
- Phorbol-12-Myristate-13-Acetate-Induced Protein 1 [NCIt concept]
- Truncated BID [NCIt concept]
is_target
- Navitoclax [NCIt concept]
- Navitoclax Dihydrochloride [NCIt concept]
- Obatoclax [NCIt concept]
- Obatoclax Mesylate [NCIt concept]

Keyword's position in hierarchy(ies) :

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