Preferred Label : Bcl-2 Homology Domain;
NCIt definition : Proteins that are related to bcl-2 are characterized by the presence of one or more
highly conserved stretches of homology with bcl-2, designated BH1, BH2, BH3, BH4.
These domains control the ability of these proteins to homo- and heterodimerize with
other proteins. Competitive dimerization between family members is thought to regulate
their function as regulators of apoptosis.;
Origin ID : C13911;
UMLS CUI : C1511077;
Semantic type(s)
- is_structural_domain_or_motif_of_gene_product
