" /> Bcl-2-Like Protein 1 - CISMeF





Preferred Label : Bcl-2-Like Protein 1;

NCIt synonyms : BCL-X Long Protein; Bcl2-L-1; BCL-X; BCL2L1; BCL2-Like 1, Long Isoform; Apoptosis Regulator Bcl-X; BCL-X Protein; BCL-XL Protein; Bcl2-Related Protein, Long Isoform; BCL2-Related Protein 1, Long Isoform; B-Cell Lymphoma-Extra Large; BCL-X(L); Bcl-XL;

NCIt definition : Bcl-2-like protein 1 (233 aa, 26 kDa) is encoded by the human BCL2L1 gene. This protein is involved in the modulation of apoptosis.;

NCIt note : Like bcl-2 bcl-xL acts as a repressor of apoptosis. bcl-xL mediates the closure of the mitochondrial porin channel VDAC and thus regulates the release of cytochrome c during apoptosis.; Bcl-2-like protein 1 has three isoforms that result from alternative splicing, Bcl-X(L), Bcl-X(S) and Bcl-X(beta). This concept describes the properties of the Bcl-X(L) isoform. (UniProt);

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15/05/2024


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