NCIt synonyms : BAD; Bcl-XL/Bcl-2-Associated Death Promoter; BCL-X/BCL-2 Binding Protein; BCL2-Binding Component 6; BAD Protein; BCL2-Binding Protein; Bcl2-L-8; BCL2-Antagonist of Cell Death; Bcl-2-Like Protein 8;
NCIt definition : Bcl2 antagonist of cell death (168 aa, 18 kDa) is encoded by the human BAD gene.
This protein is involved in the mediation of apoptosis.;
NCIt note : This protein is a member of the BCL-2 family. It positively regulates cell apoptosis
by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor
activity. Proapoptotic activity of this protein is regulated through its phosphorylation.
(from RefSeq Summary);