Bcl-X(S) - CISMeF

Preferred Label : Bcl-X(S);

NCIt synonyms : BCL-Xs Protein; Bcl-XS; BCL2-Related Protein 1, Short Isoform; Bcl2-Related Protein, Short Isoform; BCL-X Short Isoform; BCL2-Like 1, Short Isoform; BCL2L1;

NCIt definition : Bcl-X(S) (170 aa, 19 kDa) is encoded by the human BCL2L1 gene. This protein plays a role in the modulation of apoptosis.;

NCIt note : bcl-xS has been shown to inhibit the ability of bcl-2 and bcl-xL to enhance the survival of cells.; Bcl-X(S) is an isoform of Bcl-2-like protein 1 that results from alternative splicing.;

Details

Origin ID

C20415;

UMLS CUI

C5441634;

Currated CISMeF NLP mapping
- bcl-XS protein [MeSH concept]
False automatic mappings
- bcl-X protein [MeSH concept]
- bcl-x protein [MeSH Descriptor]
OMIM relation
- Bcl2-like 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- bcl-XS protein [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Apoptosis Regulation Gene [NCIt concept]
- BCL2L1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_associated_anatomy
- Outer Mitochondrial Membrane [NCIt concept]
gene_product_has_biochemical_function
- Apoptosis Promoter [NCIt concept]
- Regulatory Protein [NCIt concept]
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- BCL-2 Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- BH3 Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Apoptosis [NCIt concept]
- Positive Regulation of Apoptosis [NCIt concept]

Keyword's position in hierarchy(ies) :

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