Proto-Oncogene proteins c-bcl-2

Preferred Label : Proto-Oncogene proteins c-bcl-2;

MeSH definition : Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.;

MeSH synonym : bcl 2 proto oncogene proteins; c bcl 2 proteins; c-bcl-2, proto-oncogene proteins; proto-oncogene proteins, bcl-2; c-bcl-2 proteins; bcl-2 proto-oncogene proteins; proto oncogene proteins c bcl 2;

DeCS synonym : BCL2 Proteins; BCL2 Family Proteins;

MeSH Hyperonym : B-Cell leukemia 2 family proteins; B Cell Leukemia 2 Family Proteins; BCL2 Family Proteins; Family Proteins, BCL2; Proteins, BCL2 Family; BCL2 Proteins; Proteins, BCL2;

Is substance : O;

Details

Origin ID

D019253;

UMLS CUI

C0107696;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- agonists [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Apoptosis Regulator Bcl-2 [NCIt concept]
- BCL-2 Family Protein [NCIt concept]
Indexing information
- 4-(4-chlorophenyl)-3-(3-(4-(4-(4-((4-(dimethylamino)-1-(phenylthio)but-2-yl)amino)-3-nitrophenylsulfonamido)phenyl)piperazin-1-yl)phenyl)-5-ethyl-1-methyl-1H-pyrrole-2-carboxylic acid [MeSH Supplementary Concept]
- 6,6',7,7'-tetrahydroxy-3,3'-dimethyl-5,5'-bis(4-methylphenethyl)-2,2'-binaphthyl-1,1',4,4'-tetraone [MeSH Supplementary Concept]
- ABT-737 [MeSH Supplementary Concept]
- BCL2L2 protein, human [MeSH Supplementary Concept]
- BM-957 [MeSH Supplementary Concept]
- Bcl-2 protein, human herpesvirus 8 [MeSH Supplementary Concept]
- Bcl2l2 protein, mouse [MeSH Supplementary Concept]
- Bik protein, mouse [MeSH Supplementary Concept]
- LCL161 [MeSH Supplementary Concept]
- TM 179 [MeSH Supplementary Concept]
- TW-37 compound [MeSH Supplementary Concept]
- bax-associated protein P16, mouse [MeSH Supplementary Concept]
- meiogynin A [MeSH Supplementary Concept]
- navitoclax [MeSH Supplementary Concept]
Record concept(s)
- B-Cell leukemia 2 family proteins [MeSH concept]
- Proto-Oncogene proteins c-bcl-2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- BCL2 protein, human [MeSH Supplementary Concept]
- BCL2-like 10 protein [MeSH Supplementary Concept]
- BCL2-related protein A1 [MeSH Supplementary Concept]
- BCL2L12 protein, human [MeSH Supplementary Concept]
- BCL2L13 protein, human [MeSH Supplementary Concept]
- BCL2L13 protein, mouse [MeSH Supplementary Concept]
- BCL2L14 protein, human [MeSH Supplementary Concept]
- BCL2L14 protein, mouse [MeSH Supplementary Concept]
- BCL2L15 protein, human [MeSH Supplementary Concept]
- BNIP1 protein, human [MeSH Supplementary Concept]
- BOK protein, human [MeSH Supplementary Concept]
- Bcl-2psi protein, human [MeSH Supplementary Concept]
- Bcl2 protein, mouse [MeSH Supplementary Concept]
- Bcl2 protein, rat [MeSH Supplementary Concept]
- Bcl2L12 protein, mouse [MeSH Supplementary Concept]
- Bcl2l13 protein, rat [MeSH Supplementary Concept]
- Bcl2l15 protein, mouse [MeSH Supplementary Concept]
- Bcl2l2 protein, rat [MeSH Supplementary Concept]
- Bnip1 protein, rat [MeSH Supplementary Concept]
- Bnip2 protein, rat [MeSH Supplementary Concept]
- Ced-9 protein, C elegans [MeSH Supplementary Concept]
- Nr13 protein, chicken [MeSH Supplementary Concept]
- PMAIP1 protein, human [MeSH Supplementary Concept]
- Pmaip1 protein, mouse [MeSH Supplementary Concept]
- Pmaip1 protein, rat [MeSH Supplementary Concept]
- RTL10 protein, human [MeSH Supplementary Concept]
- bcl2a protein, zebrafish [MeSH Supplementary Concept]
- bhp2 protein, geodia cydonium [MeSH Supplementary Concept]
- bok protein, mouse [MeSH Supplementary Concept]
- buffy protein, drosophila [MeSH Supplementary Concept]
- pmaip1 protein, zebrafish [MeSH Supplementary Concept]
See also
- genes, bcl-2 [MeSH Descriptor]
See also inter- (CISMeF)
- senolytic [SYNODOS term]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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