genes, bcl-2 - CISMeF

Preferred Label : genes, bcl-2;

MeSH definition : The B-cell leukemia/lymphoma-2 genes, responsible for blocking apoptosis in normal cells, and associated with follicular lymphoma when overexpressed. Overexpression results from the t(14;18) translocation. The human c-bcl-2 gene is located at 18q24 on the long arm of chromosome 18.;

MeSH synonym : bcl 2 genes; bcl-2 gene; bcl-2 genes; gene, bcl-2; genes, bcl 2;

CISMeF synonym : bcl-2;

MeSH hyponym : c-bcl-2 genes; Gene, c-bcl-2; Genes, c-bcl-2; c bcl 2 Genes; c-bcl-2 Gene; c-bcl-2 Proto-Oncogenes; Proto-Oncogene, c-bcl-2; Proto-Oncogenes, c-bcl-2; c bcl 2 Proto Oncogenes; c-bcl-2 Proto-Oncogene;

MeSH annotation : bcl stands for B-Cell Leukemia;

Wikipedia link : https://en.wikipedia.org/wiki/Genes, bcl-2;

Details

Origin ID

D019254;

UMLS CUI

C0376515;

Allowable qualifiers
- drug effects [MeSH Qualifier]
- ethics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- immunology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Apoptosis Regulator Bcl-2 [NCIt concept]
- B-cell cll/lymphoma 2 [OMIM Phenotype]
- BCL2 [LOINC component]
- BCL2 Gene [NCIt concept]
- BCL2 apoptosis regulator [ORDO Gene]
- BCL2 gene [LOINC component]
- BCL2 gene [LOINC part]
- obsolete apoptogenic cytochrome c release channel activity [GO term]
- oncogene protein bcl-2 [SNOMED Notion]
Currated CISMeF NLP mapping
- BCL2 wt Allele [NCIt concept]
Record concept(s)
- c-bcl-2 genes [MeSH concept]
- genes, bcl-2 [MeSH concept]
See also
- Proto-Oncogene proteins c-bcl-2 [MeSH Descriptor]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
UMLS correspondences (same concept)
- B-cell cll/lymphoma 2 [OMIM Phenotype]
- BCL2 [LOINC component]
- BCL2 Gene [NCIt concept]
- BCL2 apoptosis regulator [ORDO Gene]
- BCL2 apoptosis regulator [HGNC gene]
- BCL2 gene [LOINC component]

Keyword's position in hierarchy(ies) :

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