NCIt definition : This gene is involved in apoptotic regulation. Overexpression of this gene promotes
the pathogenesis of B-Cell lymphomas, due to anti-apoptotic activity.;
Alternative definition : NCI-GLOSS: A protein that helps control whether a cell lives or dies by blocking a
type of cell death called apoptosis. The gene for BCL2 is found on chromosome 18,
and transfer of the BCL2 gene to a different chromosome is seen in many B-cell leukemias
and lymphomas. This causes the BCL2 protein to be made in larger amounts, which may
keep cancer cells from dying.;